1 00:00:03,909 --> 00:00:02,310 we often talk about new and ongoing 2 00:00:05,190 --> 00:00:03,919 experiments onboard the station but 3 00:00:07,030 --> 00:00:05,200 today we're going to talk about one 4 00:00:09,190 --> 00:00:07,040 that's complete and now providing some 5 00:00:11,270 --> 00:00:09,200 interesting results laurie meings at the 6 00:00:12,549 --> 00:00:11,280 payload operations integration center at 7 00:00:14,549 --> 00:00:12,559 the marshall space flight center in 8 00:00:16,790 --> 00:00:14,559 huntsville alabama is going to tell us 9 00:00:18,630 --> 00:00:16,800 more about the integrated cardiovascular 10 00:00:22,230 --> 00:00:18,640 experiment 11 00:00:25,029 --> 00:00:22,240 was recently named one of the most 12 00:00:26,950 --> 00:00:25,039 compelling studies from the iss today we 13 00:00:29,189 --> 00:00:26,960 learn more about this study and how the 14 00:00:32,310 --> 00:00:29,199 results are already helping folks here 15 00:00:36,229 --> 00:00:33,990 so the integrated cardiovascular study 16 00:00:37,350 --> 00:00:36,239 was one done to look at the long-term 17 00:00:39,430 --> 00:00:37,360 effects of 18 00:00:41,430 --> 00:00:39,440 space flight on heart 19 00:00:43,350 --> 00:00:41,440 size heart function 20 00:00:45,830 --> 00:00:43,360 and how those interplay with the risk 21 00:00:48,310 --> 00:00:45,840 for cardiac arrhythmias 22 00:00:50,310 --> 00:00:48,320 why was it important to study this in 23 00:00:51,350 --> 00:00:50,320 space yeah it was important because we 24 00:00:53,430 --> 00:00:51,360 know from 25 00:00:55,029 --> 00:00:53,440 ground-based analogs for space flight 26 00:00:57,029 --> 00:00:55,039 bed rest studies 27 00:00:58,869 --> 00:00:57,039 and some flight studies that the heart 28 00:01:00,630 --> 00:00:58,879 tends to get smaller 29 00:01:02,069 --> 00:01:00,640 with less activity 30 00:01:03,990 --> 00:01:02,079 you know in the past the countermeasures 31 00:01:05,990 --> 00:01:04,000 in space weren't as good and astronauts 32 00:01:07,910 --> 00:01:06,000 hearts would shrink the muscle would get 33 00:01:09,190 --> 00:01:07,920 smaller the heart is muscle and like any 34 00:01:10,950 --> 00:01:09,200 other muscle the more you work it the 35 00:01:12,870 --> 00:01:10,960 bigger it gets and the less you work it 36 00:01:14,230 --> 00:01:12,880 the more it atrophies 37 00:01:16,550 --> 00:01:14,240 so the astronauts hearts would get 38 00:01:19,350 --> 00:01:16,560 smaller the volume in the hearts would 39 00:01:21,270 --> 00:01:19,360 get smaller and there was one report of 40 00:01:22,789 --> 00:01:21,280 a cardiac arrhythmia on an astronaut who 41 00:01:25,270 --> 00:01:22,799 was on the mirror space station about 42 00:01:27,830 --> 00:01:25,280 two months into his stay so the concern 43 00:01:30,310 --> 00:01:27,840 was that these changes in heart function 44 00:01:32,310 --> 00:01:30,320 and size could lead to possible 45 00:01:33,990 --> 00:01:32,320 arrhythmias and 46 00:01:36,469 --> 00:01:34,000 besides just the arrhythmias lead to 47 00:01:37,270 --> 00:01:36,479 problems when you land from space you 48 00:01:38,870 --> 00:01:37,280 know 49 00:01:41,510 --> 00:01:38,880 spending six months in space going from 50 00:01:43,830 --> 00:01:41,520 earth to mars landing having to function 51 00:01:45,510 --> 00:01:43,840 especially in an emergency situation is 52 00:01:47,429 --> 00:01:45,520 very important 53 00:01:49,590 --> 00:01:47,439 the study had 13 astronauts four of them 54 00:01:51,830 --> 00:01:49,600 women they came from expedition 20 all 55 00:01:53,429 --> 00:01:51,840 the way through expedition 34. there was 56 00:01:55,510 --> 00:01:53,439 a lot of pre-work for this bed rest 57 00:01:58,230 --> 00:01:55,520 studies where we had patients spend five 58 00:02:00,310 --> 00:01:58,240 weeks in bed do supine cycling 59 00:02:03,030 --> 00:02:00,320 rowing orgometry all these things versus 60 00:02:06,310 --> 00:02:03,040 controls looking at exercise changes 61 00:02:08,790 --> 00:02:06,320 with heart function and muscle thickness 62 00:02:10,949 --> 00:02:08,800 so i know you have results now but i'm 63 00:02:12,790 --> 00:02:10,959 kind of curious you had four women 64 00:02:13,910 --> 00:02:12,800 the rest men were there any difference 65 00:02:15,589 --> 00:02:13,920 there 66 00:02:17,270 --> 00:02:15,599 you know so far we haven't really seen a 67 00:02:19,430 --> 00:02:17,280 difference between the men and women but 68 00:02:22,470 --> 00:02:19,440 it's not a large number of either and so 69 00:02:24,390 --> 00:02:22,480 it's hard to say that we've had enough 70 00:02:26,710 --> 00:02:24,400 to find that difference but i think 71 00:02:28,710 --> 00:02:26,720 important that in what we've seen 72 00:02:30,150 --> 00:02:28,720 it looks about the same interestingly 73 00:02:31,990 --> 00:02:30,160 heart function 74 00:02:34,390 --> 00:02:32,000 before and after four to six months of 75 00:02:35,990 --> 00:02:34,400 spaceflight really stays the same 76 00:02:38,229 --> 00:02:36,000 there's no change in how well the heart 77 00:02:39,670 --> 00:02:38,239 squeezes how much blood it pumps how 78 00:02:41,030 --> 00:02:39,680 thick the muscle gets and i think that 79 00:02:42,630 --> 00:02:41,040 really speaks to how well the 80 00:02:44,550 --> 00:02:42,640 countermeasure is on the space station 81 00:02:46,790 --> 00:02:44,560 right now and they have two hours of 82 00:02:48,470 --> 00:02:46,800 exercise time built into the system not 83 00:02:49,430 --> 00:02:48,480 sure that it's always done but it what 84 00:02:51,990 --> 00:02:49,440 they do 85 00:02:53,270 --> 00:02:52,000 seems to be very effective 86 00:02:55,589 --> 00:02:53,280 what do you hope 87 00:02:56,790 --> 00:02:55,599 comes from this experiment what should 88 00:02:58,470 --> 00:02:56,800 come out of that and why should people 89 00:03:00,390 --> 00:02:58,480 on earth care about it the two things 90 00:03:01,350 --> 00:03:00,400 that i'm most concerned into this study 91 00:03:03,589 --> 00:03:01,360 is 92 00:03:05,830 --> 00:03:03,599 long duration space flight and if we go 93 00:03:07,509 --> 00:03:05,840 through with interplanetary travel 94 00:03:09,910 --> 00:03:07,519 near earth objects 95 00:03:12,070 --> 00:03:09,920 than to make sure that the heart isn't 96 00:03:14,390 --> 00:03:12,080 compromised in such a way over 97 00:03:16,390 --> 00:03:14,400 six months in space that that the 98 00:03:18,630 --> 00:03:16,400 astronaut can't function when they land 99 00:03:20,550 --> 00:03:18,640 and i think that's very important 100 00:03:22,710 --> 00:03:20,560 besides that there are some 101 00:03:23,670 --> 00:03:22,720 results that are relevant to earth right 102 00:03:25,270 --> 00:03:23,680 now 103 00:03:26,869 --> 00:03:25,280 for example one of them is athletes the 104 00:03:28,710 --> 00:03:26,879 way the athlete heart changes with 105 00:03:29,670 --> 00:03:28,720 exercise training and when they stop 106 00:03:31,350 --> 00:03:29,680 training 107 00:03:33,110 --> 00:03:31,360 is very relevant to the information we 108 00:03:35,030 --> 00:03:33,120 get from the space station and vice 109 00:03:36,949 --> 00:03:35,040 versa we're learning constantly more 110 00:03:39,910 --> 00:03:36,959 things about it that we can apply to 111 00:03:41,910 --> 00:03:39,920 athletes who come in with heart problems 112 00:03:43,509 --> 00:03:41,920 in the same way there's a 113 00:03:45,350 --> 00:03:43,519 population of patients who have 114 00:03:47,750 --> 00:03:45,360 something called potts disease postural 115 00:03:49,670 --> 00:03:47,760 orthostatic tachycardia syndrome and 116 00:03:51,830 --> 00:03:49,680 these are mostly women 117 00:03:53,990 --> 00:03:51,840 they're young usually and they have 118 00:03:56,550 --> 00:03:54,000 difficulty standing upright for very 119 00:03:58,710 --> 00:03:56,560 long periods of time 120 00:04:00,149 --> 00:03:58,720 historically they've exercised a lot and 121 00:04:02,229 --> 00:04:00,159 then something happens and they stop 122 00:04:04,229 --> 00:04:02,239 they get pregnant they get injured and 123 00:04:06,070 --> 00:04:04,239 when they stop exercising their hearts 124 00:04:07,429 --> 00:04:06,080 shrink just like we worry about in the 125 00:04:09,429 --> 00:04:07,439 astronauts 126 00:04:10,710 --> 00:04:09,439 well using the exercise program we 127 00:04:12,550 --> 00:04:10,720 developed in bed rest and have been 128 00:04:14,070 --> 00:04:12,560 using to help the astronauts on the 129 00:04:15,830 --> 00:04:14,080 space station we made an exercise 130 00:04:17,749 --> 00:04:15,840 program for these pots patients and it 131 00:04:19,590 --> 00:04:17,759 has 132 00:04:20,629 --> 00:04:19,600 been a great cure for many of the 133 00:04:21,670 --> 00:04:20,639 patients 134 00:04:23,430 --> 00:04:21,680 and 135 00:04:24,629 --> 00:04:23,440 very pleased with the outcome of that 136 00:04:26,950 --> 00:04:24,639 the exercise is able to make their 137 00:04:28,629 --> 00:04:26,960 hearts larger make them stronger and now 138 00:04:30,870 --> 00:04:28,639 they're able to lead more 139 00:04:33,590 --> 00:04:30,880 normal realistic lives 140 00:04:34,950 --> 00:04:33,600 so how does the common everyday person 141 00:04:36,950 --> 00:04:34,960 learn about these countermeasures learn 142 00:04:38,230 --> 00:04:36,960 about the exercise programs 143 00:04:39,909 --> 00:04:38,240 i think part of the outreach of this is 144 00:04:41,430 --> 00:04:39,919 for specifically the pots program there 145 00:04:43,830 --> 00:04:41,440 are a few national centers that really 146 00:04:45,749 --> 00:04:43,840 focus on potts patients but besides that 147 00:04:48,310 --> 00:04:45,759 i think an important idea is that 148 00:04:50,469 --> 00:04:48,320 exercise is beneficial for anybody who's 149 00:04:53,110 --> 00:04:50,479 aging healthy aging 150 00:04:54,230 --> 00:04:53,120 population needs to be exercising we 151 00:04:55,830 --> 00:04:54,240 know that 152 00:04:57,510 --> 00:04:55,840 the amount of fitness somebody has in 153 00:04:59,590 --> 00:04:57,520 mid-life really relates to long-term 154 00:05:00,710 --> 00:04:59,600 mortality and the kind of exercise the 155 00:05:02,469 --> 00:05:00,720 astronauts are doing on the space 156 00:05:05,270 --> 00:05:02,479 station keeps their hearts strong and 157 00:05:07,189 --> 00:05:05,280 flexible and young and if everybody 158 00:05:09,430 --> 00:05:07,199 can start to move that way then 159 00:05:13,510 --> 00:05:09,440 people will be more functional as they 160 00:05:15,029 --> 00:05:13,520 age happier as they age feel better 161 00:05:16,950 --> 00:05:15,039 so i better get out of here as quick as 162 00:05:18,790 --> 00:05:16,960 i can and go for a run you're taking a 163 00:05:20,230 --> 00:05:18,800 live look now at the payload operations 164 00:05:21,350 --> 00:05:20,240 integration center busy at work this 165 00:05:22,469 --> 00:05:21,360 morning helping with some of those 166 00:05:24,150 --> 00:05:22,479 robonaut 167 00:05:25,430 --> 00:05:24,160 activities and anything else that the